APPLICATIONS
昆虫疾病模型
常见的果蝇（Drosophila melanogaster）为我们对果蝇和人类共享的高度保守的疾病途径的理解提供了希望。利用昆虫作为疾病模型是一种具有成本效益的治疗发现机会，包括中枢神经系统疾病、炎症性疾病、心血管疾病、癌症和糖尿病。热量测定或小型昆虫呼吸代谢测定可以作为药物筛选的有效工具，取代或增强体外小分子研究。
Important System Considerations
- 测量和控制大气气体浓度，包括水蒸气
- 代谢测量
- 进食行为
Sable SOlutions
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Relevant Publications
Relevant Publications
Ma, J., Benson, A. K., Kachman, S. D., Jacobsen, D. J., & Harshman, L. G. (2013). Drosophila melanogaster Selection for Survival after Infection with Bacillus cereus Spores: Evolutionary Genetic and Phenotypic Investigations of Respiration and Movement. International journal of evolutionary biology, 2013.
Ridley, E. V., Wong, A. C., Westmiller, S., & Douglas, A. E. (2012). Impact of the resident microbiota on the nutritional phenotype of Drosophila melanogaster. PLoS One, 7(5), e36765.
Avanesian, A., Khodayari, B., Felgner, J. S., & Jafari, M. (2010). Lamotrigine extends lifespan but compromises health span in Drosophila melanogaster. Biogerontology, 11(1), 45-52.